Hensol - Newport Gwent Dragons back Hallam Amos has withdrawn from Wales's squad for the end-of-year Tests due to a shoulder injury, the Welsh Rugby Union announced on Tuesday.
Amos, who can play wing or full-back, sustained the injury during Saturday's one-sided 32-8 loss to Australia at Cardiff's Principality Stadium.
His place in the squad has been taken by uncapped 18-year-old Ospreys wing Keelan Giles, who has been training with the group since the start of the campaign.
Scrumhalf Rhys Webb is a doubt for this Saturday's clash with Argentina after hurting his ankle against the Wallabies. Tomos Williams has been called up to provide cover.
Wales are without a win since beating Italy in their final game of this year's Six Nations Championship and have won just three of their last 12 Tests.
They are also due to host Japan and South Africa later in November.
Updated Wales squad
Wings/full-backs: Alex Cuthbert (Cardiff Blues), Keelan Giles (Ospreys), Leigh Halfpenny (Toulon/FRA), George North (Northampton/ENG), Liam Williams (Scarlets)
Centres: Cory Allen (Cardiff Blues), Jonathan Davies (Scarlets), Jamie Roberts (Harlequins/ENG), Scott Williams (Scarlets)
Flyhalves: Gareth Anscombe (Cardiff Blues), Dan Biggar (Ospreys), Sam Davies (Ospreys)
Scrumhalves: Gareth Davies (Scarlets), Rhys Webb (Ospreys), Lloyd Williams (Cardiff Blues), Tomos Williams (Cardiff Blues)
Back rows: Dan Baker (Ospreys), Taulupe Faletau (Bath/ENG), James King (Ospreys), Dan Lydiate (Ospreys), Ross Moriarty (Gloucester/ENG), Justin Tipuric (Ospreys), Sam Warburton (Cardiff Blues, capt)
Second rows: Jake Ball (Scarlets), Luke Charteris (Bath/ENG), Bradley Davies (Ospreys), Alun Wyn Jones (Ospreys), Rory Thornton (Ospreys)
Hookers: Scott Baldwin (Ospreys), Kristian Dacey (Cardiff Blues), Ken Owens (Scarlets)
Props: Scott Andrews (Cardiff Blues), Tomas Francis (Exeter/ENG, Rhys Gill (Cardiff Blues), Gethin Jenkins (Cardiff Blues), Samson Lee (Scarlets), Nicky Smith (Ospreys)