Cape Town - Uruguay had moments of encouragement, but in the end Australia cantered through to a 65-3 win in this Rugby World Cup clash at Villa Park on Sunday.
The Wallabies ran in 11 tries and had wrapped up the bonus point inside the opening 30 minutes.
They will now turn their attention to Saturday's clash at Twickenham when they take on tournament hosts England.
Scorers:
Australia 65 (31)
Tries: Sean McMahon (2), Joseph Tomane, Dean Mumm, Henry Speight, Ben McCalman (2), Drew Mitchell (2), Matt Toomua, Tevita Kuridrani
Conversions: Quade Cooper (5)
Uruguay 3 (3)
Penalty: Felipe Berchesi