Cardiff - Wales fullback Lee Byrne will miss next month's Tests against Australia, South Africa and Fiji because of a broken hand.
The British and Lions international fractured the third metacarpal in his right hand playing for club side Ospreys on Sunday.
The Welsh Rugby Union says Byrne has only "an outside chance" of being available for Wales' final Test of the year against New Zealand on November 27.
Back-row forward Rob McCusker has withdrawn from the squad to have hernia surgery.
Cardiff Blues' Chris Czekaj has been called up to replace Byrne.
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