Steyn replaces Tim Swiel in the number ten jersey while Heimar Williams steps in at inside centre alongside Paul Jordaan for their tour opener.
In other changes to the side that started against the Highlanders last week, Jean Deysel and Bismarck du Plessis are back from niggles.
More to follow
Teams:
Rebels
TBA
Sharks
15. Lwazi Mvovo, 14. Odwa Ndungane, 13. Paul Jordaan, 12. Heimar Williams, 11. JP Pietersen, 10. Francois Steyn, 9. Charl McLeod, 8. Ryan Kankowski, 7. Jean Deysel, 6. Marcell Coetzee, 5. Stephan Lewies, 4. Willem Alberts, 3. Jannie du Plessis, 2. Bismarck du Plessis (captain), 1. Tendai Mtawarira
Substitutes: 16. Kyle Cooper, 17. Dale Chadwick, 18. Lourens Adriaanse, 19. Etienne Oosthuizen, 20. Keegan Daniel, 21. Cobus Reinach, 22. Fred Zeilinga, 23. SP Marais