Cape Town - The Springboks have suffered a significant blow with the news that flank Jaco Kriel is out of their year-end European tour with a knee injury.
Kriel sustained a grade two tear of his left MCL playing club rugby in Japan at the weekend.
The 27-year-old has returned to Johannesburg for treatment and will be out of action for approximately four weeks.
Kriel was playing for the Kubota Spears and was scheduled to join the Springbok squad after their match against the Barbarians in London on November 5.
The Boks are yet to name a replacement for Kriel.
After the match against Barbarians, the Boks will face England (London, November 12), Italy (Florence, November 19) and Wales (Cardiff, November 26).
South Africa squad v Barbarians:
Lourens Adriaanse, Nizaam Carr, Uzair Cassiem, Eben Etzebeth, Lizo Gqoboka, Lood de Jager, Malcolm Marx, Bongi Mbonambi, Oupa Mohoje, Tendai Mtawarira, Trevor Nyakane, Jean-Luc du Preez, Roelof Smit, RG Snyman, Adriaan Strauss (captain), Pieter-Steph du Toit, Thomas du Toit
Damian de Allende, Ruan Combrinck, Faf de Klerk, Cheslin Kolbe, Jesse Kriel, Patrick Lambie, Rudy Paige, Sergeal Petersen, Rohan Janse van Rensburg, Tian Schoeman, Jamba Ulengo, Francois Venter, Piet van Zyl
Note: No foreign-based players available for Barbarians match
South Africa squad v England, Italy and Wales
Willem Alberts, Eben Etzebeth, Lood de Jager, Steven Kitshoff, Vincent Koch, Malcolm Marx, Bongi Mbonambi, Oupa Mohoje, Franco Mostert, Tendai Mtawarira, Trevor Nyakane, Jannie du Plessis, Jean-Luc du Preez, Roelof Smit, Adriaan Strauss (captain), Pieter-Steph du Toit, Warren Whiteley
Damian de Allende, Ruan Combrinck, Faf de Klerk, Johan Goosen, Bryan Habana, Elton Jantjies, Jesse Kriel, Patrick Lambie, Lionel Mapoe, Rudy Paige, Sergeal Petersen, JP Pietersen, Willie le Roux, Francois Venter, Piet van Zyl