Paris - France captain Thierry Dusautoir has been ruled out of the November internationals with a knee injury, the team announced on Tuesday.
Dusautoir's place in the initial 33-man squad will be taken by Toulouse team-mate Yannick Nyanga, who won the last of his 25 caps in the third-place playoff against Argentina in the 2007 World Cup.
Dusautoir, capped 54 times for France, twisted his knee in a tackle in Toulouse's 33-21 victory over Treviso in Heineken Cup action on Saturday.
Les Bleus' autumn international series kicks off against Australia on November 10, before matches against Argentina and Samoa on the following weekends.