The Currie Cup log leaders included five forwards and two backline specialists in their list of replacements for the match with most of the focus expected to be on centre Doppies La Grange.
La Grange returns after a prolonged hamstring injury which he picked up during the team's second round victory against Griquas.
Lock Wikus van Heerden is also back in the team after he withdrew from their previous match against Western Province at the last minute.
Teams
Lions: 15 Jaco Taute, 14 Deon van Rensburg, 13 Lionel Mapoe, 12 Alwyn Hollenbach, 11 Michael Killian, 10 Elton Jantjies, 9 Michael Bondesio, 8 Josh Strauss (captain), 7 Derick Minnie, 6 Cobus Grobbelaar, 5 Franco van der Merwe, 4 Wikus van Heerden, 3 Patric Cilliers, 2 Bandise Maku, 1 JC Janse van Rensburg.
Substitutes: 16 Martin Bezuidenhout, 17 Jacobie Adriaanse, 18 Johan Snyman, 19 Michael Rhodes, 20 Warren Whiteley, 21 Doppies La Grange, 22 Burton Francis
Sharks
TBA