The Northern Cape outfit beat the Golden Lions 42-32 in Johannesburg on Friday to record the side's first victory of the tournament, with winger Jannie Boshoff the only casualty from the Lions fixture.
Boshoff enjoyed a solid evening against the Lions, but Human was forced to replace the speedster with the experienced Luzuko Vulindlu.
Vulindlu played in Griquas' first Currie Cup game against the Blue Bulls, but was injured in the process.
"It is very disappointing for Jannie that he got injured again," Human said on Monday.
"He played very well against the Lions and will be sorely missed against the Sharks.
"Luckily we've got Luzuko back. He was impressive against the Bulls before he got injured."
Having started poorly, Griquas seemed to be heading for relegation, but the five points they gained against the Lions puts them back in the hunt, with only eight points the difference between them and the top placed Sharks.
"We gained some much needed momentum against the Lions," Human said.
"Yes, there were still a few areas of concern, but we've looked at that this week.
"The team has been retained as much as possible to ensure we keep that momentum going. We need to keep going forward. We need to keep on winning."
Teams:
Griquas: 15 Willie le Roux, 14 Luzuko Vulindlu, 13 Jean Stemmet, 12 Walter Venter, 11 Rocco Jansen, 10 Francois Brummer, 9 Marnus Hugo, 8 Leon Karemaker, 7 Wesley Wilkins, 6 Marnus Schoeman, 5 Martin Muller, 4 Ligtoring Landman, 3 Lourens Adriaanse, 2 Ryno Barnes (captain), 1 Steph Roberts
Substitutes: 16 Simon Westraadt, 17 Ivann Espag, 18 Frikkie Spies, 19 Justin Downey, 20 Jacques Coetzee, 21 Marnitz Boshoff, 22 Richard Lawson
Sharks:
TBA