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Deysel steps off the bench to start in place of Kankowski, who has been ruled out for four weeks with a broken thumb.
Alistair Hargreaves takes Deysel's place on the bench.
Sharks coach John Plumtree has made two other changes to the starting XV, as the title holders look to recover from a loss to log leaders the Lions last week.
Lock Jandre Marais replaces Anton Bresler, who moves down to the bench, and prop Eugene van Staden joins the starting team in place of Wiehann Herbst in another straight swap.
Skipper Keegan Daniel has recovered from an ankle injury and the flanker will fill his usual place in the starting team.
Teams:
Sharks: 15 Louis Ludik, 14 Sibusiso Sithole, 13 Stefan Terblanche, 12 Meyer Bosman, 11 Lwazi Mvovo, 10 Frederic Michalak, 9 Charl McLeod, 8 Jean Deysel, 7 Marcell Coetzee, 6 Keegan Daniel (captain), 5 Ross Skeate, 4 Jandre Marais, 3 Eugene van Staden, 2 Craig Burden, 1 Dale Chadwick
Substitutes: 16 Kyle Cooper, 17 Wiehahn Herbst, 18 Anton Bresler, 19 Alistair Hargreaves, 20 Jacques Botes, 21 Conrad Hoffmann, 22 Adrian Jacobs
Blue Bulls: 15 Jurgen Visser, 14 Akona Ndungane, 13 Zane Kirchner, 12 Wynand
Olivier, 11 Bjorn Basson, 10 Louis Fouch, 9 Jano Vermaak, 8 CJ Stander, 7
Dewald Potgieter, 6 Warwick Tecklenburg, 5 Juandre Kruger, 4 Flip van
der Merwe, 3 Werner Kruger, 2 Gary Botha (captain), 1 Dean Greyling
Substitutes: 16 Willie Wepener, 17 Rossouw de Klerk, 18 Gerrit-Jan van Velze, 19 Arno Botha, 20 Dustin Jinka, 21 Francois Brummer, 22 Francois Venter
