Details of the "Big Little Men" bill were announced in Johannesburg on Monday.
Golden Gloves promoter Rodney Berman said an IBO junior flyweight title fight between Hekkie Budler and Gideon Buthelezi would top the black-tie box-and-dine extravaganza.
It has been reported that former multiple world champion Matlata has been left nearly destitute as a result of hospital bills after suffering from double pneumonia.
"Initially it was intended to feature up-and-coming heavyweight Flo Simba on the programme," said Berman.
"But it was then decided it would be more appropriate to highlight a fight in the weight division in which Baby Jake excelled.
"And it would defeat the purpose of the occasion if we paid out a huge slice of the proceedings on purse money for a string of high-profiled fighters.
"Baby Jake was Budler's hero and Hekkie wants to help his role model," added Berman.
"There has been a great deal of discussion as to whether Budler or Buthelezi, who are IBO champions in different divisions, is the more accomplished boxer.
"This will be an appropriate and opportune time to settle the arguments."
Berman said numerous entertainers had come forward to help the former champion.