United have lost two of their last four outings and both of those losses came away from home. Jose Mourinho still has question marks over his best XI and how to work Paul Pogba into the mix. Now, he must go - as the reigning Europa League winner - to the home of the 2016 Europa League champions.
Sevilla are not the team in this competition that they transform into when playing in Europe’s B-list event. They have lost all three of their ties at this stage including to Leicester last year. The hosts can however lean on history with their record against English sides firmly in the positive; Manchester City the only side to beat them on Andalusian soil.
The Red Devils are indeed the side needing to reverse some rotten away form. They’ve won just two of nine away games (D4 L3) and have an overall record on the road which reads W3 D10 L10.
Fans of the English side can look to Mourinho’s sound record against Sevilla, the Portuguese has tasted defeat just once to Sevilla in eight outings scoring almost four goals a game in that time.
The performance of Romelu Lukaku against Huddersfield in the FA Cup will please Mourinho with Alexis Sanchez getting better acquainted with his new surroundings all the time.
Pogba - whether briefly sick or just disgruntled over Sanchez’ arrival - should return for this clash and will be key to deciding the contest on Wednesday. The Frenchman, when he decides, is one of the best players in the world and could rip Sevilla apart on his own. Throw in Lukaku and Sanchez and United could wrap up the tie like Liverpool did against Porto last week.
You can back Pogba to score anytime - and at the same time quash and of the rumours he’s unhappy - at 34/10 or jump on the 9/2 on offer for the match to be a draw at half-time and then the visitors to win it in the second 45.