Intermittent rain is predicted for the first four days of the Test which does not bode well for the amount of cricket that will be played.
When play does get underway the home side will want to put a run of poor form behind them.
The hosts have lost seven consecutive matches, two twenty20 and five one-day internationals, to the Proteas.
The Windies’ cause is not helped by the absence of the injured duo of batsman Ramnaresh Sarwan and paceman Jerome Taylor.
South Africa will have to make a decision on whether to pick JP Duminy ahead of Ashwell Prince while all-rounder Ryan McLaren will battle it out with left-arm swing bowler Lonwabo Tsotsobe for the third seamer spot.
Teams:
West Indies (possible) - Chris Gayle (captain), Travis Dowlin, Shivnarine Chanderpaul, Darren Bravo, Brendan Nash, Dwayne Bravo, Denesh Ramdin (wk), Darren Sammy, Shane Shillingford, Kemar Roach, Ravi Rampaul.
South Africa (possible) - Graeme Smith (captain), Alviro Petersen, Hashim Amla, Jacques Kallis, AB de Villiers, JP Duminy, Mark Boucher (wk), Paul Harris, Dale Steyn, Morne Morkel, Lonwabo Tsotsobe.