Durban - David Miller was a late injury withdrawal as the Proteas lost the toss and were asked to bat first in the third and final Twenty20 International against the West Indies at Kingsmead in Durban on Wednesday.
The big-hitting middle order batsman has a back problem and was replaced by a surprise face in the South Africa XI, JP Duminy, who is back again from a lengthy spell on the sidelines.
Imran Tahir also misses out for the hosts and is among three changes, the other being captain Faf du Plessis.
Justin Ontong is the stand-in skipper, while Wayne Parnell and Aaron Phangiso also play.
The big news for the tourists is the absence of Chris Gayle, man-of-the-match in the previous two games.
The opener has been rested, while Denesh Ramdin and Jason Holder also miss out.
West Indies have already won the series after winning the opening two games.
South Africa: Morne van Wyk (wk), Reeza Hendricks, Rilee Rossouw, JP Duminy, Justin Ontong (capt), Farhaan Behardien, David Wiese, Wayne Parnell, Kyle Abbott, Aaron Phangiso, Marchant de Lange.
West Indies: Lendl Simmons, Dwyane Smith, Marlon Samuels, Dwayne Bravo, Kieron Pollard, Andre Fletcher (wk), Darren Sammy (capt), Andre Russell, Carlos Brathwaite, Ashley Nurse, Sheldon Cottrell.